Basically,
BCAAs (branched chain amino acids) is composed of leucine, isoleucine and
valine. These are essential amino acids not produced by the body and have to be
sourced from outside. They have been in the market since 1996 for treating
liver diseases like cirrhosis. Today, BCAA
supplement is used by body builders for exercise purposes.
They
are the largest collection of amino acids in the body, making up to 35% of the
muscle protein.
Since
used by body fitness aficionados and by athletes, there had been many other health
benefits attributed to them.
Exercise performance
Today,
exercise buffs know that exercise leads to amino acid usage. BCAAs are rapidly
depleted during exercise which shows the beneficial effects of BCAAs. In a
controlled trial on marathon runners, BCAA supplementation showed improved
mental performance. Running times of slower athletes improved.
In
another study, BCAA supplementation increased the muscle strength of the
athletes compared to other supplements (whey protein and carbohydrate
supplements). It also increased power output in another study, although
decreased fatigue and exertion may be the cause of the power rise.
Fatigue reduction / endurance increase
In
another study, marathoners with BCAA supplementation experienced fatigue
reduction after a race and in another the fatigue decreased by an average of
17.2%.
In
the same manner, BCAA supplementation can increase endurance. The runners given
BCAA supplements ran better times for two consecutive days in a row in both
5,000 and 10,000 m races.
There
is also an increase in lactate threshold in a study. Lactate threshold measures
endurance capacity as any exercise below the threshold does not build up the muscles.
The
study also showed that oxygen consumption increased by 13%.
Liver health
In
another study, BCAA supplementation not only increase nutritional status but
also improved sleep and decreased fatigue in liver cirrhosis patients. In
another one, 20 chronic hepatitis patients and 100 cirrhosis patients had
greatly increased albumin in their blood after BCAA supplementation after which
both liver diseases had declined.
The
liver survival rate without any detriment was around 63.6% with BCAA help.
Kidneys
BCAA
supplementation had reduced the chances of kidney failure by up to 40%. It
increases amino acids levels but not protein intake, which decreases kidney
damage.
The
supplements also improved appetite and nutrition in dialysis patients.
Energy increase
When
there is a state of increased amino acid levels, the amino acids will compete
with glucose to provide energy. It becomes as secondary source of energy. In
one study, people with high levels of amino acids require 35% less glucose.
Isoleucine
decreased glucose usage by 20% in the blood and 71% in the muscles. Both isoleucine
and valine can also be converted into glucose.
Insulin resistance / sleep improvement
Insulin
resistance increase blood sugar levels. Patients suffering from either insulin
resistance or hepatitis C were provided with BCAA supplementation. The muscle
insulin resistance improved in around half of the patients.
Some
patients with kidney problems developed sleep disorders and reduced sleep
quality and time. Taking BCAA supplement at night increased their REM (rapid
eye movement) and decreased end-tidal CO2 levels which is important for
dreaming.
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